4-(2-Methoxy-2-oxoethyl)benzoic acid(CAS: 87524-66-1)

4-(2-Methoxy-2-oxoethyl)benzoic acid is a white crystalline solid with a molecular weight of approximately 228.22 g/mol. It has low solubility in water but good solubility in organic solvents like ethanol and acetone. Chemically, it is reactive and easily forms salts with bases. It can undergo esterification and amide formation reactions.

4-(2-Methoxy-2-oxoethyl)benzoic acid can be synthesized by esterification of 2-methoxyacetic acid with benzoic anhydride. The reaction typically involves heating the mixture under reflux conditions in the presence of a catalyst like sulfuric acid. The yield is usually around 75-85% with good selectivity.

4-(2-Methoxy-2-oxoethyl)benzoic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a monomer or additive. Additionally, it is used in the production of sensors and as a reagent in analytical chemistry and semiconductor manufacturing.

When handling 4-(2-Methoxy-2-oxoethyl)benzoic acid, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from heat sources. In case of spill, use appropriate spill cleanup methods as outlined in the SDS. Always conduct reactions in a fume hood to minimize inhalation risk.