tert-butyl 4-[4-[6-amino-5-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]-3-pyridyl]pyrazol-1-yl]piperidine-1-carboxylate(CAS: 877399-51-4)

The compound is a crystalline solid with a molecular weight of approximately 629.35 g/mol. It has low water solubility and moderate solubility in common organic solvents like DMSO. Chemically, it is reactive towards nucleophiles and bases, making it suitable for various synthetic applications. It exhibits good stability under normal storage conditions but is sensitive to strong acids and bases.

This compound is typically synthesized via a multi-step process involving the formation of an ethoxy derivative of a pyridine ring, followed by its coupling with a pyrazole moiety, and finally, an amino substitution. The reaction yields a high purity product with good selectivity, and the overall yield is around 70-75%. Commonly used catalysts include organometallic reagents and phase transfer catalysts.

This compound finds application in the pharmaceutical industry for the development of new drugs due to its structural complexity and potential biological activity. It may also be used in the synthesis of other chemical intermediates and in materials science for its unique chemical properties.

When handling this compound, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from strong acids and bases. In case of a spill, it should be handled in a fume hood using appropriate cleanup procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.