(1r,4r)-4-methylcyclohexan-1-amine, trans(CAS: 2523-55-9)

(1R,4R)-4-Methylcyclohexan-1-amine, trans is a colorless to light yellow liquid at room temperature. Its molecular weight is approximately 121.23 g/mol. It has a moderate solubility in water (13.7 g/L at 20°C) and good solubility in organic solvents. It is moderately reactive with strong acids and bases. This compound is known for its stability under normal conditions but should be stored away from strong oxidizing agents to prevent decomposition.

(1R,4R)-4-Methylcyclohexan-1-amine, trans can be synthesized by the reduction of 4-methylcyclohexanone with hydrogen in the presence of a catalyst such as palladium on carbon. This process is carried out under mild conditions, and the yield can be up to 95%. The trans isomer is preferred over the cis isomer due to its higher reactivity and better physical properties.

(1R,4R)-4-Methylcyclohexan-1-amine, trans is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drug molecules. It also finds applications in the polymer industry, where it serves as a monomer for certain polymerization reactions. Additionally, it is used in the production of sensors and in the electronics industry as a component in semiconductor materials.

When handling (1R,4R)-4-methylcyclohexan-1-amine, trans, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be cleaned up using appropriate absorbent materials, and the area should be flushed with water. In case of inhalation, seek medical attention immediately. Safety data sheets (SDS) should be consulted for detailed emergency procedures and handling guidelines.