4-Bromo-1(2H)-isoquinolinone(CAS: 3951-95-9)

4-Bromo-1(2H)-isoquinolinone (CAS: 3951-95-9) is a crystalline compound with a molecular weight of approximately 229.03 g/mol. It has a high solubility in organic solvents like dichloromethane and low solubility in water. It is moderately reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored away from moisture and heat.

4-Bromo-1(2H)-isoquinolinone is typically synthesized by bromination of 1(2H)-isoquinolinone using N-bromosuccinimide (NBS) in the presence of a radical initiator like AIBN. The reaction is conducted in an inert atmosphere to prevent decomposition. The yield is generally high, and the product can be purified by recrystallization from organic solvents.

4-Bromo-1(2H)-isoquinolinone (CAS: 3951-95-9) is primarily used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). It also finds applications in the production of organic semiconductors and as a precursor in polymer chemistry. Its unique properties make it valuable in research and development for various chemical applications.

When handling 4-Bromo-1(2H)-isoquinolinone (CAS: 3951-95-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from moisture and heat. Fume hoods should be used during handling to minimize exposure. In case of spills, neutralize with water and dispose of according to local regulations. Always consult a safety data sheet (SDS) for detailed handling and disposal information.