3-(5-Methyl-4-phenyl-1,2-oxazol-3-yl)benzenesulfonamide(CAS: 1373038-56-2)

3-(5-Methyl-4-phenyl-1,2-oxazol-3-yl)benzenesulfonamide is a crystalline solid with a molecular weight of approximately 326.33 g/mol. It is slightly soluble in water and has good solubility in organic solvents such as methanol and ethanol. Chemically, it is stable and shows limited reactivity under normal conditions. The compound can be characterized by its distinctive UV-Vis absorption spectrum and NMR spectroscopic data.

3-(5-Methyl-4-phenyl-1,2-oxazol-3-yl)benzenesulfonamide can be synthesized via a multi-step process involving the reaction of 5-methyl-4-phenyl-1,2-oxazole with phenylsulfamic acid hydrazide. The key steps include the formation of a sulfonamide linkage under basic conditions, followed by purification and crystallization. This compound is often obtained with good yield and selectivity.

3-(5-Methyl-4-phenyl-1,2-oxazol-3-yl)benzenesulfonamide is used in the pharmaceutical industry for its potential as an intermediate in drug synthesis. It is also explored in polymer science for its functional groups, which can be utilized in various applications. Additionally, it may have applications in sensor technology and semiconductor fabrication processes.

When handling 3-(5-Methyl-4-phenyl-1,2-oxazol-3-yl)benzenesulfonamide, it is important to wear appropriate personal protective equipment such as gloves and goggles. Handle in a well-ventilated area or a fume hood. In case of spill, neutralize with an appropriate chemical and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.