2-Chloro-4-iodonicotinonitrile(CAS: 1171919-75-7)

2-Chloro-4-iodonicotinonitrile (CAS: 1171919-75-7) is a crystalline solid with a molecular weight of approximately 326.02 g/mol. It has a low solubility in water and is more soluble in organic solvents such as acetone and ethanol. The compound is moderately reactive, particularly towards nucleophiles, and can undergo substitution reactions. It tends to decompose at high temperatures, releasing toxic gases.

2-Chloro-4-iodonicotinonitrile is typically synthesized through the reaction of 4-chloronicotinonitrile with iodine in the presence of a suitable base such as potassium carbonate. The process involves the substitution of the chlorine atom with an iodine atom, yielding the desired product with good selectivity. The reaction is carried out under anhydrous conditions to avoid side reactions and is best performed in an inert atmosphere.

2-Chloro-4-iodonicotinonitrile (CAS: 1171919-75-7) is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various bioactive compounds and can be used in the development of new drugs. Additionally, it finds applications in the production of dyes, pigments, and other organic compounds.

When handling 2-Chloro-4-iodonicotinonitrile (CAS: 1171919-75-7), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area, preferably in a fume hood, to minimize inhalation risks. Ensure proper storage in a dry, cool place away from moisture and incompatible materials. Always refer to the Safety Data Sheet (SDS) for detailed guidelines on handling and disposal.