Methyl 3-chloroisonicotinate(CAS: 98273-79-1)

Methyl 3-chloroisonicotinate (CAS: 98273-79-1) is a white crystalline solid at room temperature. Its molecular weight is approximately 177.58 g/mol. The compound is slightly soluble in water but soluble in organic solvents like ethanol and acetone. It is highly reactive due to the presence of the chloro and ester functional groups, making it prone to hydrolysis and nucleophilic substitution reactions.

Methyl 3-chloroisonicotinate (CAS: 98273-79-1) is commonly synthesized through the condensation of 3-chloroisonicotinic acid with methyl alcohol in the presence of a strong base like sodium hydroxide. The reaction is carried out in a solvent such as methanol or ethanol, often at elevated temperatures. The yield is typically around 75-85%, and the reaction is highly selective, making it a reliable method for production.

Methyl 3-chloroisonicotinate (CAS: 98273-79-1) finds applications in various industries. It is used in pharmaceuticals for intermediate synthesis, in polymers for plasticizers and additives, and in sensors for detection of specific chemicals. Additionally, it is employed in the synthesis of semiconductors and as a reagent in organic chemistry.

When handling Methyl 3-chloroisonicotinate (CAS: 98273-79-1), it is essential to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from sources of heat. Handling should be conducted in a fume hood to minimize exposure to vapors. In case of spill, immediate action should be taken according to the Safety Data Sheet (SDS) guidelines to ensure safety.