2-Amino-4-pentenoic acid(CAS: 7685-44-1)

2-Amino-4-pentenoic acid is a white crystalline solid with a molecular weight of approximately 138.15 g/mol. It has a pKa of around 2.2 and is soluble in water. It is moderately reactive, particularly with basic substances. This compound is prone to hydrolysis and can react with carboxylic acid derivatives.

2-Amino-4-pentenoic acid can be synthesized through the condensation of acetoacetic acid and ammonia. Alternatively, it can be prepared by the reduction of 4-pentenoic acid with hydrogen in the presence of a catalyst such as palladium on carbon. The yield and selectivity of the reaction can be improved by optimizing reaction conditions.

2-Amino-4-pentenoic acid is primarily used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the polymer industry as a monomer and in sensor technology for its reactivity with certain compounds. Additionally, it has potential uses in semiconductor processing due to its chemical properties.

When handling 2-Amino-4-pentenoic acid, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. This compound should be stored in a cool, dry place away from oxidizing agents and acids. Spills should be cleaned up carefully using appropriate chemicals and procedures as outlined in a safety data sheet (SDS). Fume hoods should be used during handling to minimize inhalation risk.