Sodium benzotriazol-2-ide(CAS: 15217-42-2)

Sodium benzotriazol-2-ide (CAS: 15217-42-2) is a white crystalline solid with a molecular weight of approximately 209.24 g/mol. It has a solubility of about 4 g/L in water and 100 g/L in hot ethanol. It is highly reactive and used in organic synthesis as a coupling reagent. It is also a weak base and aprotic solvent.

Sodium benzotriazol-2-ide (CAS: 15217-42-2) is typically synthesized by the reaction of sodium hydride with 2-aminobenzene-1,3-diyl bis(triethyltin) in an inert solvent such as tetrahydrofuran (THF). The reaction is carried out under anhydrous conditions to avoid decomposition. The yield is around 70-80%.

Sodium benzotriazol-2-ide (CAS: 15217-42-2) is widely used in pharmaceuticals, particularly in the synthesis of pharmaceutical intermediates. It is also used in polymer chemistry for the modification of polymers and in the electronics industry for the production of semiconductors and sensors.

Sodium benzotriazol-2-ide (CAS: 15217-42-2) should be handled with care. It is recommended to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the use of a fume hood for handling this reagent. Spills should be cleaned up using appropriate spill response materials. It is advised to consult the Safety Data Sheet (SDS) for detailed safety information.