2,4,6-Trifluoro-N-{6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl}benzamide(CAS: 439239-90-4)

2,4,6-Trifluoro-N-{6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl}benzamide (CAS: 439239-90-4) is a white to off-white crystalline solid with a molecular weight of approximately 444.36 g/mol. It has low solubility in water but is soluble in organic solvents such as methanol and acetonitrile. The compound is moderately reactive and can undergo nucleophilic substitution and condensation reactions. It is stable in air but should be stored in a dry environment to prevent moisture absorption.

2,4,6-Trifluoro-N-{6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl}benzamide (CAS: 439239-90-4) is synthesized via a multistep process involving coupling of 2,4,6-trifluorobenzamide with 6-(1-methyl-4-piperidinyl)pyridine-3-carbonyl chloride. The reaction typically requires the use of a coupling agent like HATU and a base such as DIPEA. The yield is around 70-80%, and the selectivity is good, with minimal side products.

2,4,6-Trifluoro-N-{6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl}benzamide (CAS: 439239-90-4) is primarily used in the pharmaceutical industry for the development of new drugs. It also has potential applications in the polymer industry, where it can be used as a precursor for functionalized polymers. Additionally, it may be utilized in the production of sensors and semiconductors due to its unique chemical properties.

When handling 2,4,6-Trifluoro-N-{6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl}benzamide (CAS: 439239-90-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry environment, and fume hoods should be used during handling to minimize inhalation risks. In case of a spill, immediately clean up the area using appropriate absorbent materials and dispose of the waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.