6-Fluoro-4-oxo-4H-chromene-2-carboxylic acid(CAS: 99199-59-4)

6-Fluoro-4-oxo-4H-chromene-2-carboxylic acid is a white crystalline solid with a high melting point of about 285-287°C. Its molecular weight is approximately 254.13 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound has good stability at room temperature but can be sensitive to moisture and light.

6-Fluoro-4-oxo-4H-chromene-2-carboxylic acid is usually synthesized via a multi-step process involving the reduction of 6-fluoro-4-oxo-4H-chromene followed by carboxylation. Key catalysts include palladium-based catalysts, and the process involves careful control of reaction conditions to achieve high selectivity and yield.

6-Fluoro-4-oxo-4H-chromene-2-carboxylic acid finds application in pharmaceuticals, where it serves as an important intermediate in drug synthesis. It is also used in the development of sensors and semiconductors for its unique optical and electronic properties.

When handling 6-Fluoro-4-oxo-4H-chromene-2-carboxylic acid, it is important to use appropriate personal protective equipment (PPE) including gloves, goggles, and lab coats. Store the compound in a cool, dry place away from direct sunlight and moisture. In case of spill, use an appropriate absorbent material and consult the safety data sheet (SDS) for further guidance.