Methyl 1H-indol-3-ylacetate(CAS: 1912-33-0)

Methyl 1H-indol-3-ylacetate (CAS: 1912-33-0) is a crystalline solid with a molecular weight of approximately 184.26 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. It is moderately reactive, particularly towards nucleophiles and bases.

Methyl 1H-indol-3-ylacetate (CAS: 1912-33-0) is typically synthesized via a condensation reaction between indole and acetic anhydride. The reaction is catalyzed by an acid, such as sulfuric acid, and proceeds with moderate to good yield. Selectivity is high, and the product is purified by recrystallization.

Methyl 1H-indol-3-ylacetate (CAS: 1912-33-0) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those requiring indole derivatives. It is also utilized in the sensor technology sector for developing chemical sensors and in the semiconductor industry for specific applications requiring indole-based materials.

When handling Methyl 1H-indol-3-ylacetate (CAS: 1912-33-0), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The substance should be used in a well-ventilated area or a fume hood. Spills should be cleaned up immediately with appropriate absorbent materials. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.