8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone(CAS: 1201438-56-3)

8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone is a solid with a crystalline form. The molecular weight is approximately 510.71 g/mol. It is slightly soluble in ethanol and acetone, but insoluble in water. The compound is stable under normal conditions but reacts with strong bases. Given its chemical reactivity, it is important to handle in a fume hood.

8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone is synthesized by the reaction of 2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone with thionyl chloride in the presence of a catalyst. The synthesis typically yields a high purity product with good selectivity and yield. Detailed procedures can be found in literature sources.

This compound is primarily used in the pharmaceutical industry for its potential as an active pharmaceutical ingredient. It may also find applications in the development of new drug candidates. Additionally, it could be used in research related to organic chemistry and medicinal chemistry.

When handling 8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone, it is crucial to use personal protective equipment (PPE) such as gloves and goggles. The compound should be stored in a cool, dry place and handled in a fume hood. In case of a spill, use appropriate spill cleanup procedures and refer to the Safety Data Sheet (SDS) for detailed guidance.