1,3-Difluoroacetone(CAS: 453-14-5)

1,3-Difluoroacetone (CAS: 453-14-5) is a colorless to slightly yellow liquid with a molecular weight of 114.04 g/mol. It has a melting point of -72°C and a boiling point of 85.4°C. This compound is poorly soluble in water but miscible with ethanol and ether. It is reactive under certain conditions, showing reactivity towards nucleophiles and electrophiles.

1,3-Difluoroacetone (CAS: 453-14-5) can be synthesized via the hydrofluorination of acetaldehyde using a platinum catalyst. The reaction is conducted under high pressure and temperature, with selectivity towards the desired product. Other methods include the fluorination of acetone with hydrogen fluoride or other fluorinating agents.

1,3-Difluoroacetone (CAS: 453-14-5) is used in the pharmaceutical industry for the synthesis of various drugs, in the polymer industry as a monomer for polymers, and in the chemical industry for the production of other organic compounds. It is also used in analytical chemistry as a reagent in sensors and semiconductors.

When handling 1,3-Difluoroacetone (CAS: 453-14-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be stored in a well-ventilated area, preferably under a fume hood. In case of spillage, use appropriate containment and clean up using absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.