N-[(3R,4R)-1-benzyl-4-methyl-3-piperidyl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine(CAS: 477600-73-0)

N-[(3R,4R)-1-benzyl-4-methyl-3-piperidyl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a crystalline solid with a molecular weight of approximately 432.46 g/mol. It has a low water solubility and exhibits good reactivity towards nucleophiles. This compound features a pyrrolo[2,3-d]pyrimidine skeleton with substituents that enhance its biological activity.

N-[(3R,4R)-1-benzyl-4-methyl-3-piperidyl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is synthesized via multistep reactions involving piperidine and benzylamine as key precursors. The synthesis typically employs standard organic techniques such as reflux, purification by column chromatography, and use of common catalysts like triphenylphosphine. The overall yield is around 70-80%, with high selectivity towards the desired product.

N-[(3R,4R)-1-benzyl-4-methyl-3-piperidyl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is primarily used in the pharmaceutical industry, where it serves as a key intermediate in the development of novel drugs. It is also relevant to the chemical industry for its potential use in polymer synthesis and as a precursor for various functional materials. Additionally, it finds applications in sensor technology and as a component in semiconductor devices.

When handling N-[(3R,4R)-1-benzyl-4-methyl-3-piperidyl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled with caution, using absorbent materials and following laboratory safety procedures. Ensure that a Safety Data Sheet (SDS) is readily accessible for reference and follow all local regulations regarding chemical handling and disposal.