7-(1,3-Benzoxazol-2-ylsulfanyl)-3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine(CAS: 722456-31-7)

7-(1,3-Benzoxazol-2-ylsulfanyl)-3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine is a crystalline compound with a molecular weight of approximately 418.48 g/mol. It has low solubility in water but is soluble in organic solvents such as methanol and acetonitrile. This compound is highly reactive and susceptible to hydrolysis under basic conditions. It shows good stability under acidic conditions and moderate stability under neutral conditions.

7-(1,3-Benzoxazol-2-ylsulfanyl)-3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine is synthesized through a multi-step process involving the reaction of 2-mercaptobenzoxazole and benzylamine followed by nucleophilic aromatic substitution. The synthesis typically uses palladium catalysts and provides good selectivity and yield under mild conditions. The process is optimized for high purity and can be scaled up for industrial applications.

7-(1,3-Benzoxazol-2-ylsulfanyl)-3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine is primarily used in the pharmaceutical industry for the development of new drugs. It also finds applications in the synthesis of organic semiconductors and as a precursor in the development of polymer-based composites. Additionally, it is explored for its potential in sensor technology due to its unique electronic properties.

When handling 7-(1,3-Benzoxazol-2-ylsulfanyl)-3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood to avoid inhalation of potential vapors. Store it in a cool, dry place away from moisture and direct sunlight. In case of a spill, use appropriate spill kits and consult the Safety Data Sheet (SDS) for specific cleanup procedures.