7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(1H)-one(CAS: 62458-96-2)

7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(1H)-one (CAS: 62458-96-2) is a crystalline solid with a molecular weight of approximately 262.27 g/mol. It has a solubility of about 20 mg/mL in water and is slightly soluble in common organic solvents. It is chemically reactive towards nucleophiles, particularly amines and thiols, and can be used as an intermediate in organic synthesis.

7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(1H)-one is often synthesized via a multi-step process involving the condensation of 2-benzylamino-4,5-dihydro-1H-pyridin-3-one with a suitable reagent. Common methods include using acetaldehyde in the presence of a base, followed by hydrolysis to form the final product. High yields and good selectivity are achieved under optimized conditions.

7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(1H)-one (CAS: 62458-96-2) is primarily used in pharmaceuticals for the synthesis of various drug candidates, particularly those targeting nucleic acid binding and DNA repair mechanisms. It is also used in polymer chemistry for the development of functional materials and in sensor technology for detecting specific biological molecules.

When handling 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(1H)-one (CAS: 62458-96-2), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to prevent inhalation. In the event of a spill, it should be cleaned up immediately using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.