1-Bromo-4-(prop-2-yn-1-yloxy)benzene(CAS: 33133-45-8)

1-Bromo-4-(prop-2-yn-1-yloxy)benzene (CAS: 33133-45-8) is a crystalline solid with a molecular weight of approximately 240.04 g/mol. It has limited water solubility, with a solubility of around 0.015 g/100 mL at 20°C. The compound is known for its reactivity, particularly towards nucleophilic substitution reactions. It is not flammable but caution is advised due to its reactivity.

1-Bromo-4-(prop-2-yn-1-yloxy)benzene is typically synthesized through the reaction of bromine with 4-(prop-2-yn-1-yloxy)benzene in the presence of an appropriate catalyst. The reaction is carried out in a solvent such as acetone. The yield and selectivity of the reaction can be enhanced by optimizing reaction conditions and using efficient catalysts.

1-Bromo-4-(prop-2-yn-1-yloxy)benzene is used in the pharmaceutical and chemical industries for the synthesis of various organic compounds. It plays a role in the development of new materials and drugs. Due to its reactivity, it is also utilized in polymer chemistry and as a precursor in the production of functional materials in the semiconductor industry.

When handling 1-Bromo-4-(prop-2-yn-1-yloxy)benzene (CAS: 33133-45-8), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.