3-Aminoisonicotinonitrile(CAS: 78790-79-1)

3-Aminoisonicotinonitrile (CAS: 78790-79-1) is a crystalline compound with a molecular weight of approximately 159.14 g/mol. It has a high solubility in water and organic solvents. Chemically, it is moderately reactive, particularly under basic conditions. It exhibits good thermal stability but can undergo hydrolysis under acidic conditions.

3-Aminoisonicotinonitrile (CAS: 78790-79-1) is typically synthesized via a multi-step process starting from nicotinonitrile and ammonia. The reaction involves a nucleophilic substitution where ammonia acts as the nucleophile to replace a cyano group. Catalysts and promoters are used to enhance selectivity and yield, with overall production being efficient under mild conditions.

3-Aminoisonicotinonitrile (CAS: 78790-79-1) finds applications in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients. It is also used in the polymer industry for functionalizing polymers. Additionally, it is applied in the development of sensors and as a precursor in semiconductor manufacturing processes.

When handling 3-Aminoisonicotinonitrile (CAS: 78790-79-1), it is crucial to wear appropriate Personal Protective Equipment (PPE), including gloves and goggles. Work should be conducted in a well-ventilated area or fume hood. Spills should be immediately contained and cleaned up using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.