3-(Methylamino)-1-phenyl-1-propanone hydrochloride (1:1)(CAS: 2538-50-3)

3-(Methylamino)-1-phenyl-1-propanone hydrochloride is a white to off-white crystalline solid with a molecular weight of approximately 244.29 g/mol. It has a high solubility in water and methanol. Chemically, it is a weak acid due to the presence of the hydrochloride salt. It is reactive towards bases and can undergo hydrolysis under basic conditions. Its boiling point is around 186°C and melting point is 134-136°C.

3-(Methylamino)-1-phenyl-1-propanone hydrochloride is typically synthesized by the reaction of 3-(methylamino)-1-phenyl-1-propanone with hydrochloric acid. The reaction is carried out under mild conditions, and the yield is usually around 80-90%. The product can be purified by recrystallization from a suitable solvent.

3-(Methylamino)-1-phenyl-1-propanone hydrochloride is used primarily in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also used in the polymer industry for the preparation of functional polymers with specific properties. Additionally, it has applications in the sensor and semiconductor industries due to its chemical reactivity and solubility properties.

When handling 3-(methylamino)-1-phenyl-1-propanone hydrochloride, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up using appropriate absorbent materials, and the area should be flushed with water. It is recommended to consult the Safety Data Sheet (SDS) for more detailed handling and storage information.