2-(Bromomethyl)-1-fluoro-3-(trifluoromethyl)benzene(CAS: 239087-08-2)

CAS Number
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Basic Information
Molecular Formula
C8H5BrF4
Molecular Weight
257.02 g/mol
Physical Properties
Melting Point
42.0 to 46.0 deg-C
Boiling Point
186 ºC
Chemical Identifiers
SMILES
C1=CC(=C(C(=C1)F)CBr)C(F)(F)F
InChIKey
RINUERVPFANASB-UHFFFAOYSA-N
Database References
MDL Number
MFCD00082477
FAQ
2-(Bromomethyl)-1-fluoro-3-(trifluoromethyl)benzene is a colorless liquid with a molecular weight of approximately 311.97 g/mol. It has a solubility of about 0.05 g/L in water and is highly soluble in organic solvents. Chemically, it is relatively stable but can react with nucleophiles under certain conditions.
How is 2-(Bromomethyl)-1-fluoro-3-(trifluoromethyl)benzene (CAS: 239087-08-2) typically synthesized?
2-(Bromomethyl)-1-fluoro-3-(trifluoromethyl)benzene is synthesized via a bromination reaction of 1-fluoro-3-(trifluoromethyl)benzene, followed by a coupling reaction. The synthesis typically involves palladium catalysts and requires controlled conditions to achieve high yield and selectivity.
2-(Bromomethyl)-1-fluoro-3-(trifluoromethyl)benzene is used in the pharmaceutical industry for the synthesis of certain drug candidates. It is also applied in the polymer industry for the development of specialized polymers and in the electronics sector for use in semiconductor materials.
When handling 2-(Bromomethyl)-1-fluoro-3-(trifluoromethyl)benzene, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a fume hood to minimize exposure. Spills should be handled with appropriate absorbent materials and the substance should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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