7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid(CAS: 15180-02-6)

7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is a crystalline solid with a molecular weight of approximately 315.33 g/mol. It has a low solubility in water but good solubility in organic solvents. The compound is relatively stable but reactive towards bases. It can form complexes with metal ions and undergoes acid-base reactions typical of carboxylic acids.

7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is typically synthesized through a multi-step process involving the condensation of benzylamine and ethyl-4-oxo-1,4-dihydro-1,8-naphthyridin-3-carboxylate. The reaction is catalyzed by a Lewis acid, such as aluminum chloride, and proceeds with high selectivity. The overall yield ranges from 70-85%.

7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is used in the pharmaceutical industry for its potential as a bioactive compound, in the polymer industry as a functional monomer, and in the semiconductor industry for its use in sensor applications due to its ability to form complexes with metal ions.

When handling 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place, away from moisture and acids. In case of a spill, it should be cleaned up using appropriate absorbent materials, and the area should be well ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety instructions.