N,N-Bis[3-(dimethylamino)propyl]-N',N'-dimethyl-1,3-propanediamine(CAS: 33329-35-0)

N,N-Bis[3-(dimethylamino)propyl]-N',N'-dimethyl-1,3-propanediamine is a colorless to white crystalline solid with a molecular weight of approximately 282.4 g/mol. It has a pKa of about 10.4 and is highly soluble in water and organic solvents. This compound is weakly basic and shows good reactivity in nucleophilic substitution reactions.

N,N-Bis[3-(dimethylamino)propyl]-N',N'-dimethyl-1,3-propanediamine is synthesized through a multistep process, involving the reaction of 1,3-propanediamine with dimethylamine and propylamine. Commonly, this involves heating the reactants in the presence of a catalyst, such as triethylamine, to promote the desired amide formation. The reaction yields approximately 90% of the product with good selectivity.

N,N-Bis[3-(dimethylamino)propyl]-N',N'-dimethyl-1,3-propanediamine is used in various industries, including pharmaceuticals for the synthesis of certain active pharmaceutical ingredients, polymers for producing heat-resistant resins, and sensors for detecting amines. It is also employed in the production of semiconductors for specific applications in the electronics industry.

When handling N,N-Bis[3-(dimethylamino)propyl]-N',N'-dimethyl-1,3-propanediamine, ensure the use of appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or under a fume hood to minimize inhalation. Store the compound in a cool, dry place away from direct sunlight. In case of a spill, neutralize the spill with an appropriate acid or base and dispose of it according to local regulations. Refer to the safety data sheet (SDS) for detailed information on handling and storage procedures.