(Benzyloxy)(trimethyl)silane(CAS: 14642-79-6)

(Benzyloxy)(trimethyl)silane is a colorless liquid with a molecular weight of approximately 180.24 g/mol. It has a low solubility in water but is miscible with organic solvents. Chemically, it is moderately reactive, especially under basic conditions, and can undergo substitution reactions. This compound is crystalline at temperatures below -20°C.

(Benzyloxy)(trimethyl)silane is typically synthesized by the reaction of trimethylsilyl chloride with benzyloxyamine. The process involves the formation of a silyl enol ether intermediate, followed by a rearrangement to yield the desired product. The reaction is usually catalyzed by a strong base such as sodium hydride, with a yield of around 75-85%.

(Benzyloxy)(trimethyl)silane is used in various industries, including pharmaceuticals for the synthesis of certain drugs, polymers for modifying properties, sensors for detecting specific compounds, and semiconductors for surface treatment and packaging. It serves as a reagent in organic synthesis and as a protective group in chemical reactions.

When handling (Benzyloxy)(trimethyl)silane, it is essential to wear appropriate personal protective equipment (PPE), including goggles, gloves, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be managed using appropriate absorbent materials and should be disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.