2-Bromo-3-methylaniline(CAS: 54879-20-8)

2-Bromo-3-methylaniline (CAS: 54879-20-8) is a white crystalline solid with a molecular weight of approximately 170.01 g/mol. It has a melting point of 58-60°C and is slightly soluble in water. This compound is known for its reactivity, particularly in nucleophilic substitution reactions, due to the presence of the bromine and amino groups.

2-Bromo-3-methylaniline (CAS: 54879-20-8) is typically synthesized via the bromination of 3-methylaniline using N-bromosuccinimide (NBS) as the brominating agent. The reaction is carried out in an inert solvent like dichloromethane under light or UV light exposure, yielding a high percentage of the desired product with good selectivity.

2-Bromo-3-methylaniline (CAS: 54879-20-8) is primarily used in the pharmaceutical industry for the synthesis of certain organic compounds and intermediates. It also finds applications in the production of dyes and pigments, as well as in the development of sensors and semiconductors.

When handling 2-Bromo-3-methylaniline (CAS: 54879-20-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up carefully, and the area should be decontaminated. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal guidelines.