5-methoxy-1H-indol-4-amine(CAS: 431046-37-6)

5-Methoxy-1H-indol-4-amine (CAS: 431046-37-6) has a molecular weight of approximately 171.19 g/mol. It is a white crystalline solid with a melting point around 168-169°C. The compound is slightly soluble in water but soluble in organic solvents like ethanol and acetonitrile. It is highly reactive towards acid and bases, making it suitable for various chemical transformations and applications in organic synthesis.

5-Methoxy-1H-indol-4-amine (CAS: 431046-37-6) is commonly synthesized via the reduction of 5-methoxy-1H-indol-4-one using a reducing agent like lithium aluminum hydride (LAH). The reaction typically proceeds with a moderate yield and requires careful handling to avoid over-reduction. Other methods include the direct amination of 5-methoxy-1H-indol-4-carboxylic acid, which provides higher purity products.

5-Methoxy-1H-indol-4-amine (CAS: 431046-37-6) is primarily used in the pharmaceutical industry for the synthesis of various indole derivatives with biological activities. It is also used in the field of organic electronics, particularly in the development of organic semiconductors and sensors, due to its electronic properties.

When handling 5-methoxy-1H-indol-4-amine (CAS: 431046-37-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS/SDS) for specific handling and disposal instructions.