6-Chloro-4-iodonicotinonitrile(CAS: 1061357-83-2)

6-Chloro-4-iodonicotinonitrile is a crystalline solid with a molecular weight of approximately 326.01 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetonitrile. It exhibits moderate reactivity, particularly in nucleophilic substitution reactions.

6-Chloro-4-iodonicotinonitrile can be synthesized through the nucleophilic substitution of 4-chloronicotinonitrile with iodine in the presence of a base like potassium carbonate. The reaction involves the use of a solvent such as acetonitrile and typically yields a product with high selectivity.

6-Chloro-4-iodonicotinonitrile is primarily used in the pharmaceutical industry for the synthesis of intermediates and bioactive compounds. It is also utilized in the polymer industry for the development of specific polymers and in the semiconductor industry for certain manufacturing processes.

When handling 6-Chloro-4-iodonicotinonitrile, it is important to use personal protective equipment (PPE) such as gloves and safety glasses. Work should be performed in a fume hood. Spills should be cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed safety information.