(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol(CAS: 64183-27-3)

The compound (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS: 64183-27-3) has a crystalline form and a molecular weight of approximately 331.2 g/mol. It is poorly soluble in water but soluble in organic solvents. Chemically, it is highly reactive due to the presence of the hydroxymethyl and aminopurin-9-yl groups. It exhibits good reactivity in nucleophilic substitution reactions.

This compound can be synthesized through multistep organic synthesis, involving the protection of the hydroxyl group, coupling with the 9-aminopurine, and subsequent deprotection. Commonly used catalysts include transition metals, and the process often involves high yields and good selectivity.

This compound finds application in the pharmaceutical industry, particularly in the development of antiviral and anticancer drugs. It is also used in the polymer industry for its potential in modifying polymer properties, in sensor technology for its reactivity, and in semiconductor manufacturing for its electronic properties.

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.