Compound Q&A

How is (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS: 64183-27-3) typically synthesized?

Answer

(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
This compound can be synthesized through multistep organic synthesis, involving the protection of the hydroxyl group, coupling with the 9-aminopurine, and subsequent deprotection. Commonly used catalysts include transition metals, and the process often involves high yields and good selectivity.

About

CAS No 64183-27-3
English Name (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
Molecular Formula C10H12FN5O3
Molecular Weight 269.236 g/mol
SMILES C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)F)N
InChIKey ZGYYPTJWJBEXBC-QYYRPYCUSA-N
Last Updated: 2025-09-07 10:18

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