Methyl 4-(1-bromoethyl)benzoate(CAS: 16281-97-3)

Methyl 4-(1-bromoethyl)benzoate (CAS: 16281-97-3) is a white crystalline solid with a molecular weight of approximately 250.03 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and acetone. This compound is reactive, particularly under basic conditions, and can undergo nucleophilic substitution reactions.

Methyl 4-(1-bromoethyl)benzoate is commonly synthesized via the reaction of 4-(1-hydroxyethyl)benzoic acid with bromomethyl ketone in the presence of a base such as sodium hydroxide. The reaction yields a high selectivity and good yield, making it a reliable method for preparing this compound.

Methyl 4-(1-bromoethyl)benzoate (CAS: 16281-97-3) is used in the pharmaceutical industry for the synthesis of various compounds, and in the polymer industry for specific applications requiring brominated functionalities. It is also relevant in the production of sensors and semiconductors due to its brominated structure.

Proper Personal Protective Equipment (PPE), including gloves and safety goggles, is essential when handling Methyl 4-(1-bromoethyl)benzoate (CAS: 16281-97-3). Work should be conducted in a well-ventilated fume hood. In case of spills, neutralize with an appropriate acid and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.