(E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-YL)benzylidene]piperidin-2-one(CAS: 870843-42-8)

The compound is a crystalline solid with a molecular weight of approximately 547.6 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetone. The compound exhibits moderate reactivity under acidic or basic conditions. It is susceptible to hydrolysis and should be stored in a dry, cool environment to prevent degradation.

The compound is typically synthesized through a multistep process involving the coupling of a fluorene derivative with a piperidine compound, followed by a condensation reaction with an imidazolyl benzaldehyde. The reaction is catalyzed by a palladium complex and proceeds with high selectivity and yield. The reaction conditions are optimized to ensure high purity and minimal by-products.

The compound is used in the pharmaceutical industry for the development of new drugs due to its biological activity. It also finds applications in the synthesis of certain flavor and fragrance compounds. Additionally, it can be used as a precursor in the development of materials for sensors and semiconductors.

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place and away from direct sunlight. It should be handled under a fume hood to minimize exposure to fumes. In case of a spill, it should be cleaned up carefully and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.