Ethyl 4-nitro-1H-pyrazole-3-carboxylate(CAS: 55864-87-4)

Ethyl 4-nitro-1H-pyrazole-3-carboxylate (CAS: 55864-87-4) is a crystalline compound with a molecular weight of approximately 218.12 g/mol. It has a solubility of 0.5 g/100 mL in water and exhibits moderate solubility in common organic solvents. The compound is known for its reactivity, particularly towards nucleophilic substitution and reduction reactions.

Ethyl 4-nitro-1H-pyrazole-3-carboxylate (CAS: 55864-87-4) is typically synthesized via the nitration of ethyl pyrazole-3-carboxylate. The nitration process is carried out using nitric acid in the presence of sulfuric acid as a catalyst. The yield is around 70-80% with good selectivity to the desired nitro product.

Ethyl 4-nitro-1H-pyrazole-3-carboxylate (CAS: 55864-87-4) is utilized in the pharmaceutical industry for the synthesis of various drug precursors. It is also employed in the polymer industry as a precursor for the synthesis of functionalized polymers. Additionally, it has applications in the development of gas sensors and as a precursor in semiconductor manufacturing processes.

When handling Ethyl 4-nitro-1H-pyrazole-3-carboxylate (CAS: 55864-87-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from sources of heat and ignition. In case of a spill, it should be cleaned up using appropriate absorbent materials, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.