(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine(CAS: 110429-36-2)

(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine is a white crystalline solid with a molecular weight of approximately 413.37 g/mol. It is sparingly soluble in water but soluble in organic solvents such as methanol and ethanol. Chemically, it is reactive, especially in acidic or basic conditions, and can undergo substitution reactions. It is also prone to hydrolysis under certain conditions.

(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine is synthesized through a multistep process involving the protection of the amine, introduction of the fluorophenyl group, and subsequent coupling with the benzodioxol moiety. The synthesis requires the use of catalysts like palladium complexes and protecting groups. The overall yield is typically around 50-60%.

(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine is used in the pharmaceutical industry for developing new drugs, particularly in the field of CNS (central nervous system) drugs. It is also utilized in the production of sensors and as a precursor in polymer synthesis.

When handling (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine, it is essential to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a fume hood to minimize exposure. Spills should be carefully cleaned up following the safety data sheet (SDS) guidelines. Always refer to the SDS for detailed emergency procedures and storage recommendations.