Imidazo[4,5,1-jk][1]benzazepin-2(1H)-one, 4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]-, hydrochloride (1:1), (6R,7R)-rel-(CAS: 119520-06-8)

Imidazo[4,5,1-jk][1]benzazepin-2(1H)-one, 4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]-, hydrochloride (1:1), (6R,7R)-rel- (CAS: 119520-06-8) is a white to off-white crystalline solid with a molecular weight of approximately 377.8 g/mol. It has a pKa of about 8.5 and good solubility in water and organic solvents like methanol and dimethylformamide. Reactivity is moderate, with typical hydrolysis and nucleophilic substitution reactions. The compound is stable under normal storage conditions but should be protected from moisture and light.

Imidazo[4,5,1-jk][1]benzazepin-2(1H)-one, 4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]-, hydrochloride (1:1), (6R,7R)-rel- (CAS: 119520-06-8) is typically synthesized via a multi-step process involving condensation reactions, alkylation, and hydrolysis. Commonly, the synthesis employs acyl chlorides or carboxylic acids as starting materials, using a Lewis acid catalyst like aluminum chloride or titanium(IV) isopropoxide. The yield is generally around 70-80%, with a high level of structural purity.

Imidazo[4,5,1-jk][1]benzazepin-2(1H)-one, 4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]-, hydrochloride (1:1), (6R,7R)-rel- (CAS: 119520-06-8) is used in pharmaceuticals for its potential as an anti-inflammatory and analgesic agent. It also finds applications in the development of sensors for detecting specific analytes due to its unique chemical properties. Additionally, it is explored in the field of semiconductors for its electronic properties.

When handling Imidazo[4,5,1-jk][1]benzazepin-2(1H)-one, 4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]-, hydrochloride (1:1), (6R,7R)-rel- (CAS: 119520-06-8), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work in a well-ventilated area, preferably in a fume hood, to avoid inhalation. Ensure proper storage in a cool, dry place away from direct sunlight and moisture. In case of a spill, immediately clean up using appropriate absorbents and follow laboratory safety guidelines. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.