[3-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)phenyl]boronic acid(CAS: 380430-68-2)

(3-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)phenyl)boronic acid is a white crystalline solid with a molecular weight of approximately 297.34 g/mol. It has a low solubility in water but is more soluble in organic solvents such as methanol and DMSO. This compound exhibits moderate reactivity in esterification and boronate ester formation reactions, making it useful in organic synthesis.

(3-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)phenyl)boronic acid is typically synthesized through the condensation of 2-methyl-2-propanol with 4-aminophenyl boronic acid, followed by carbonylation. The reaction is usually catalyzed by a transition metal catalyst such as palladium or ruthenium, with a yield of about 70-80%.

(3-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)phenyl)boronic acid finds applications in the pharmaceutical industry for its use as a precursor in drug synthesis. It is also employed in organic synthesis for boronate ester formation and in some cases, in the development of sensors and semiconductor materials.

When handling (3-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)phenyl)boronic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a fume hood to prevent inhalation. Spills should be wiped up with absorbent paper and disposed of according to local waste regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.