Methyl 3-chloro-2-thiophenecarboxylate(CAS: 88105-17-3)

Methyl 3-chloro-2-thiophenecarboxylate (CAS: 88105-17-3) is a crystalline solid with a molecular weight of approximately 204.61 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and dichloromethane. This compound is reactive, especially towards nucleophiles, and is susceptible to hydrolysis. It has a melting point of around 78-80°C.

Methyl 3-chloro-2-thiophenecarboxylate (CAS: 88105-17-3) can be synthesized by the condensation of 3-chloro-2-thiophenecarboxylic acid with methyl alcohol in the presence of a catalytic amount of phosphorous acid. This method provides good selectivity and yield, with mild conditions required for the reaction.

Methyl 3-chloro-2-thiophenecarboxylate (CAS: 88105-17-3) is utilized in the pharmaceutical industry for the synthesis of certain drugs and intermediates. It is also used in the polymer industry for the production of advanced polymers with specific properties. Furthermore, it has applications in the sensor and semiconductor industries for the development of specialized materials.

When handling Methyl 3-chloro-2-thiophenecarboxylate (CAS: 88105-17-3), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to the compound. Spills should be cleaned up using appropriate solvents and wearing proper protective gear. Always refer to the Safety Data Sheet (SDS) for comprehensive safety guidelines.