N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]phenyl}-5-methoxy-9-oxo-9,10-dihydro-4-acridinecarboxamide(CAS: 143664-11-3)

N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]phenyl}-5-methoxy-9-oxo-9,10-dihydro-4-acridinecarboxamide is a crystalline solid with a molecular weight of approximately 603.38 g/mol. It is sparingly soluble in common organic solvents like DMSO and methanol. Chemically, it is stable under normal conditions but may undergo hydrolysis in basic media. It reacts readily with bases and displays good reactivity towards nucleophiles.

N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]phenyl}-5-methoxy-9-oxo-9,10-dihydro-4-acridinecarboxamide is usually synthesized through a multistep process involving the coupling of an acridone derivative with a 6,7-dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl ethylamine under mild conditions. The reaction is typically catalyzed by a palladium complex and proceeds with good yield and selectivity.

N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]phenyl}-5-methoxy-9-oxo-9,10-dihydro-4-acridinecarboxamide finds applications in the pharmaceutical industry due to its potential as an anticancer agent. It is also explored in the development of sensors and semiconductors for its unique optoelectronic properties.

When handling N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]phenyl}-5-methoxy-9-oxo-9,10-dihydro-4-acridinecarboxamide, it is essential to use personal protective equipment (PPE) including gloves, goggles, and lab coats. Store it in a fume hood and avoid contact with skin and eyes. In case of spillage, immediately clean up using appropriate absorbent materials and consult the Safety Data Sheet (SDS) for further instructions.