5-Nitro-1,2-benzoxazole(CAS: 39835-28-4)

5-Nitro-1,2-benzoxazole (CAS: 39835-28-4) is a crystalline solid with a molecular weight of approximately 181.13 g/mol. It has a melting point of 242-244°C and is slightly soluble in water. This compound is relatively stable but can react with strong bases and reducing agents. It is used as a precursor in organic synthesis and in the preparation of other nitrogen-containing heterocycles.

5-Nitro-1,2-benzoxazole can be synthesized by nitration of 1,2-benzoxazole. The reaction typically involves treating 1,2-benzoxazole with a mixture of nitric acid and sulfuric acid under controlled conditions. The yield is around 75-85%, and the product can be purified by recrystallization.

5-Nitro-1,2-benzoxazole (CAS: 39835-28-4) is primarily used in the pharmaceutical and chemical industry as a precursor for the synthesis of other compounds. It is also used in the preparation of semiconductors and as a component in some polymer formulations for its electronic properties and stability.

When handling 5-Nitro-1,2-benzoxazole (CAS: 39835-28-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle it in a well-ventilated area or fume hood to avoid inhalation. In case of a spill, neutralize with an appropriate acid or base and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed safety information.