4-(trans-4-Pentylcyclohexyl)benzonitrile(CAS: 61204-01-1)

4-(trans-4-Pentylcyclohexyl)benzonitrile (CAS: 61204-01-1) is a colorless to light yellow liquid at room temperature. It has a molecular weight of approximately 222.23 g/mol and a high boiling point of 226-228°C. It is only slightly soluble in water but soluble in common organic solvents. The compound shows low reactivity under normal conditions but can undergo hydrogenation with palladium catalysts.

4-(trans-4-Pentylcyclohexyl)benzonitrile is typically synthesized via a multistep process. First, 4-pentylcyclohexanone is reacted with sodium bis(trimethylsilyl)amide (SBTMA) to form a nitrile. Then, the product is deprotected under acidic conditions. This process requires the use of appropriate solvents and catalysts to achieve good yield and selectivity.

4-(trans-4-Pentylcyclohexyl)benzonitrile (CAS: 61204-01-1) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also employed in the polymer industry as a monomer or additive due to its thermal stability and chemical resistance. Additionally, it has applications in the production of sensors and semiconductors due to its electronic properties.

When handling 4-(trans-4-Pentylcyclohexyl)benzonitrile (CAS: 61204-01-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for specific disposal instructions.