[4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate(CAS: 1146629-77-7)

(4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate is a crystalline compound with a molecular weight of approximately 328.35 g/mol. It has a pKa of around 3.5, indicating moderate acidity. The compound is slightly soluble in common organic solvents such as methanol and dichloromethane. Reactivity is moderate, with potential for nucleophilic substitution reactions. Storage should be at room temperature away from moisture and light.

(4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate can be synthesized via a multistep reaction involving the condensation of 4-(1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid with pivaloyl chloride. The process yields a 90% yield with good selectivity. This reaction is typically performed under anhydrous conditions to optimize yield and purity.

(4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate is used in the pharmaceutical industry for the synthesis of certain drugs due to its biological activity. It also finds applications in the polymer industry for the development of advanced materials. Additionally, it is explored in the sensor and semiconductor industries for its potential in electronic and chemical sensing applications.

When handling (4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store the compound in a well-ventilated area and avoid contact with skin and eyes. In case of a spill, use appropriate clean-up procedures and dispose of any contaminated materials according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.