3-[3-(Trifluoromethyl)phenyl]propanal(CAS: 21172-41-8)

3-[3-(Trifluoromethyl)phenyl]propanal (CAS: 21172-41-8) is a colorless to light yellow liquid with a molecular weight of approximately 226.15 g/mol. It has a high boiling point around 230°C and a low solubility in water. It is reactive, particularly towards nucleophiles due to the presence of the aldehyde group.

3-[3-(Trifluoromethyl)phenyl]propanal (CAS: 21172-41-8) is commonly synthesized through a condensation reaction between 3-(trifluoromethyl)benzaldehyde and propionic acid, using a strong base like sodium hydroxide as a catalyst. The reaction is carried out in an aprotic solvent at room temperature to achieve a high yield and good selectivity.

3-[3-(Trifluoromethyl)phenyl]propanal (CAS: 21172-41-8) is used in the pharmaceutical industry for the production of certain drugs, and in the chemical industry for the synthesis of polymers and sensors. It also finds applications in the semiconductor industry due to its electronic properties.

When handling 3-[3-(Trifluoromethyl)phenyl]propanal (CAS: 21172-41-8), it is essential to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to avoid inhalation of fumes. In case of a spill, immediately clean up with the appropriate absorbent material and ensure proper disposal. Always refer to the Safety Data Sheet (SDS) for detailed safety information.