1-(4-Fluorophenyl)-4-[4-(2-hydroxy-1H-benzimidazol-1-yl)-3,6-dihydro-1(2H)-pyridinyl]-1-butanone(CAS: 548-73-2)

This compound has a crystalline form with a molecular weight of approximately 435.39 g/mol. It has a low solubility in water (0.01 g/100 mL at 20°C) but is more soluble in organic solvents like dichloromethane and acetonitrile. Chemically, it is stable but may react with strong acids or bases under certain conditions. It is an important intermediate in the synthesis of various pharmaceuticals and materials.

This compound is typically synthesized via a multistep process starting from 4-fluoroaniline and 2-hydroxy-1H-benzimidazol-1-yl-3,6-dihydropyridine. The synthesis involves condensation reactions, cyclizations, and purification steps. Common catalysts and reagents include triphenylphosphine and acetic anhydride.

This compound is used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). It is also utilized in the development of sensors and materials, particularly in the field of semiconductor technology. Its unique electronic properties make it valuable in the production of advanced electronic components.

When handling this compound, it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.