1,4,7,10-Tetraazacyclododecan-1-ylacetic acid(CAS: 170454-90-7)

1,4,7,10-Tetraazacyclododecan-1-ylacetic acid (CAS: 170454-90-7) is a water-soluble compound with a molecular weight of approximately 232.25 g/mol. It crystallizes in the form of white needles and exhibits good water solubility. The compound is mildly basic due to its amine functionalities and can react with acidic compounds to form salts. It is also known for its stability under normal conditions but can degrade over time in acidic environments.

1,4,7,10-Tetraazacyclododecan-1-ylacetic acid (CAS: 170454-90-7) is synthesized through the condensation of 1,4,7,10-tetraazacyclododecane with acetic anhydride. The reaction is catalyzed by a trace amount of a Lewis acid such as aluminum chloride. The yield is typically high, and the product is isolated by recrystallization from a suitable solvent. The process requires careful control of the reaction conditions to achieve high selectivity and purity.

1,4,7,10-Tetraazacyclododecan-1-ylacetic acid (CAS: 170454-90-7) finds applications in pharmaceuticals, where it serves as a chelating agent in drug formulations. It is also used in the synthesis of polymers and as a component in sensor technologies. Additionally, it has applications in semiconductor manufacturing due to its ability to form stable complexes with metal ions, which is crucial for certain processes.

When handling 1,4,7,10-Tetraazacyclododecan-1-ylacetic acid (CAS: 170454-90-7), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat to protect against skin and eye contact. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly rinsed with water. Consult the Safety Data Sheet (SDS) for detailed emergency procedures and handling guidelines.