N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE(CAS: 53678-77-6)

N-AcetylMuramyl-L-Alanyl-D-Isoglutamine (CAS: 53678-77-6) is a crystalline compound with a molecular weight of approximately 457.4 g/mol. It has limited solubility in water and is practically insoluble in organic solvents. This compound is known to be highly reactive, particularly with nucleophiles and bases. It is susceptible to hydrolysis under basic conditions.

N-AcetylMuramyl-L-Alanyl-D-Isoglutamine (CAS: 53678-77-6) is typically synthesized through a multi-step process involving peptide coupling reactions. Key steps include the formation of the peptide bond between N-acetyl muramine and L-alanine, followed by the coupling with D-isoglutamine. The synthesis often employs coupling reagents like 1-hydroxybenzotriazole (HOBt) and N,N′-carbonyldiimidazole (CDI) with appropriate catalysis to enhance selectivity and yield.

N-AcetylMuramyl-L-Alanyl-D-Isoglutamine (CAS: 53678-77-6) is primarily used in the pharmaceutical industry, particularly in the development of vaccines and adjuvants. It also finds applications in the polymer industry for functionalization of polymer surfaces and in sensors for detection of specific biological molecules.

When handling N-AcetylMuramyl-L-Alanyl-D-Isoglutamine (CAS: 53678-77-6), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be immediately contained and cleaned up with appropriate absorbents. Refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.