5-Iodo-3-(trifluoromethyl)pyridin-2-OL(CAS: 887707-23-5)

5-Iodo-3-(trifluoromethyl)pyridin-2-ol is a crystalline compound with a molecular weight of approximately 330.01 g/mol. It exhibits low water solubility and is generally poor in organic solvents. The compound is highly reactive due to the presence of the iodo and trifluoromethyl groups, which can participate in nucleophilic and electrophilic reactions.

5-Iodo-3-(trifluoromethyl)pyridin-2-ol is typically synthesized through a multi-step process involving the bromination of 3-(trifluoromethyl)pyridin-2-ol followed by iodination. Common catalysts include palladium complexes, and high yields can be achieved with appropriate reaction conditions and purification techniques.

5-Iodo-3-(trifluoromethyl)pyridin-2-ol is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It is also utilized in the polymer industry for cross-linking applications and in the sensor industry for its unique reactivity with specific analytes.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 5-Iodo-3-(trifluoromethyl)pyridin-2-ol. Work should be conducted in a fume hood to minimize exposure. Spills should be carefully cleaned up using appropriate materials and procedures. Always refer to the Safety Data Sheet (SDS) for detailed safety information.