5-Butyl-2-(ethylamino)-6-methyl-4-pyrimidinol(CAS: 23947-60-6)

5-Butyl-2-(ethylamino)-6-methyl-4-pyrimidinol is a white crystalline solid with a molecular weight of approximately 219.27 g/mol. It has a solubility of about 10.5 mg/mL in water and is slightly soluble in ethanol. The compound is moderately reactive, especially in the presence of acids or bases. It is stable under normal conditions but may degrade at high temperatures or in strong solvents.

5-Butyl-2-(ethylamino)-6-methyl-4-pyrimidinol is typically synthesized via the reaction of 5-bromomethyl-2-ethylamino-6-methylpyrimidine with n-butyllithium followed by a Grignard reaction with butyllithium. This method yields high selectivity and a good yield of the target compound. The reaction is usually carried out in a solvent like THF under anhydrous conditions.

5-Butyl-2-(ethylamino)-6-methyl-4-pyrimidinol is used in the pharmaceutical industry for the synthesis of certain antifungal and antiviral drugs due to its antimicrobial properties. It is also utilized in the sensor industry for the development of gas sensors due to its chemical reactivity. Additionally, it has potential applications in the polymer industry as a functional monomer.

When handling 5-Butyl-2-(ethylamino)-6-methyl-4-pyrimidinol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat. In case of a spill, it should be handled carefully and neutralized with an appropriate chemical before disposal. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.