4-(Methylthio)benzaldehyde(CAS: 3446-89-7)

CAS Number
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Basic Information
Molecular Formula
C8H8OS
Molecular Weight
152.22 g/mol
Physical Properties
Melting Point
6 °C
Boiling Point
153°C/17mmHg(lit.)
Water Solubility
Not miscible in water.
Chemical Identifiers
SMILES
CSC1=CC=C(C=C1)C=O
InChIKey
QRVYABWJVXXOTN-UHFFFAOYSA-N
Database References
MDL Number
MFCD00006948
Beilstein Registry Number
636158
FAQ
4-(Methylthio)benzaldehyde (CAS: 3446-89-7) is a white or light yellow crystalline solid with a molecular weight of approximately 150.21 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophilic substitution at the sulfur atom. It can also undergo condensation reactions and is an important intermediate in organic synthesis.
4-(Methylthio)benzaldehyde is commonly synthesized via the reaction of methyl mercaptan with benzaldehyde. The reaction typically proceeds via a nucleophilic substitution at the benzaldehyde aldehyde group. Other methods include the reduction of 4-methylthioacetophenone with sodium borohydride. The yield is usually around 80-85%, and the method involves the use of a milder catalyst for better selectivity.
4-(Methylthio)benzaldehyde (CAS: 3446-89-7) finds application in various industries. It is used in pharmaceuticals for the synthesis of certain drugs. In the polymer industry, it serves as a building block for the production of functional polymers. It is also used in the production of sensors and semiconductors due to its unique chemical properties.
When handling 4-(Methylthio)benzaldehyde (CAS: 3446-89-7), it is essential to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or under a fume hood to prevent inhalation. In case of a spill, it should be cleaned up using appropriate absorbents and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
Contact Person
Mr. Wang
174160056@qq.com





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