3-Thienylacetic acid(CAS: 6964-21-2)

3-Thienylacetic acid (CAS: 6964-21-2) is a crystalline solid at room temperature with a molecular weight of 152.14 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. Chemically, it is acidic and can react with bases to form salts. It is also reactive towards nucleophiles and can undergo esterification and condensation reactions.

3-Thienylacetic acid can be synthesized via the condensation of 2-thienylacetonitrile with sodium hydroxide or by the reaction of thienylacetic anhydride with a suitable base. Common catalysts include sodium hydroxide and potassium hydroxide. The yield is typically around 75-85%, and high selectivity is achieved under mild conditions.

3-Thienylacetic acid (CAS: 6964-21-2) is used in the pharmaceutical industry for the synthesis of certain drugs, as a precursor in polymer chemistry for developing functional materials, and in the manufacturing of sensors and semiconductors due to its unique chemical properties.

When handling 3-Thienylacetic acid (CAS: 6964-21-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, well-ventilated area away from sources of ignition. In case of a spill, use appropriate spill cleanup equipment and consult the Safety Data Sheet (SDS) for specific handling instructions.