8-Chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione(CAS: 85-18-7)

8-Chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione, also known as 8-Cl-PMPA, is a purine derivative with a molecular formula of C8H7ClN5O2. It is a white crystalline solid with a melting point of 224-225°C and a density of 1.45g/cm³. This compound is widely used in pharmaceutical applications and as a research tool.

8-Chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (8-Cl-PMPA) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of drugs, particularly antivirals and antimicrobials. It is also used in research for studying purine metabolism and as a non-toxic substitute for other nucleosides.

8-Chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (8-Cl-PMPA) is generally considered safe for industrial use and research when handled with appropriate precautions. It is non-toxic and non-flammable. However, it should be used in a well-ventilated area and appropriate protective equipment should be worn to avoid skin contact and inhalation of dust. Spills should be cleaned up carefully and disposed of in accordance with local regulations.

8-Chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (8-Cl-PMPA) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in sealed, airtight containers to prevent moisture absorption. The storage temperature should not exceed 30°C, and the relative humidity should be maintained below 50% to ensure stability and prevent degradation. Proper labeling is also essential to avoid confusion with other substances.