(2R,3R)-N1,N4-Dibenzyl-2,3-dihydroxysuccinamide(CAS: 88393-56-0)

(2R,3R)-N1,N4-Dibenzyl-2,3-dihydroxysuccinamide is a white crystalline solid with a molecular weight of approximately 422.46 g/mol. It has a solubility of about 1.5 mg/mL in water and is slightly soluble in common organic solvents. It is reactive towards bases and can undergo hydrolysis. The compound is stable under normal conditions but should be protected from moisture and light.

(2R,3R)-N1,N4-Dibenzyl-2,3-dihydroxysuccinamide is typically synthesized via the condensation of benzylamine with 2,3-dihydroxysuccinic acid. The reaction is catalyzed by an appropriate base, such as triethylamine, and proceeds under mild conditions. The yield is around 85%, and the selectivity is excellent, providing a pure product with high purity.

(2R,3R)-N1,N4-Dibenzyl-2,3-dihydroxysuccinamide is used in the pharmaceutical industry for the synthesis of various drug intermediates. It is also employed in the polymer industry for the modification of polymer properties. In addition, it has applications in the production of sensors and semiconductors due to its unique chemical structure and reactivity.

When handling (2R,3R)-N1,N4-Dibenzyl-2,3-dihydroxysuccinamide, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from moisture and light. Fume hoods should be used during handling to avoid inhalation. In case of a spill, neutralize the spill with a suitable acid or base solution and dispose of it according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.